Volume, asymmetry and reciprocal relationships between paranasal sinuses: a 3D segmentation study on head CT-scans

DOI: https://doi.org/10.25241/stomaeduj.2020.7(1).art.3


Introduction Very little is known about the morphology of paranasal sinuses, especially with respect to symmetry.
Methodology The head CT-scans of 100 patients (50 male, 50 female) were retrospectively analyzed. The volume segmentation of frontal, sphenoid and maxillary sinuses was performed through semi-automatic segmentation. An asymmetry index was extracted, and differences according to sex and side were assessed through ANOVA test (p<0.05). Pearson test was applied to verify possible correlation between age and volume and asymmetry index in different paranasal sinuses and sexes (p<0.05).
Results On average, male sinuses were larger in volume than female ones (p<0.01). Generally, volumes of the three sinuses were significantly related each other in both sexes (correlation coefficients ranging between 0.34 and 0.58). In both sexes, the maxillary sinus was less asymmetric than the other two types, without significant sex-related differences (p>0.05). Significant inverse correlations between sinus volume and asymmetry index were found for the sphenoid and maxillary sinuses in males, and for the maxillary sinus in females. No correlation of sinus volume or asymmetry index with age was found, with the exception of maxillary volume/age in females.
Conclusion The present results may find practical applications in planning surgical procedures involving paranasal sinuses.

Anatomy; CT-Scan; Segmentation; Paranasal Sinuses; Surgery.