Influence of fluoride mouthwash containing nanohydroxyapatite on the dentin interface of direct restorations: A randomized controlled crossover in situ study

Introduction: Toevaluatetheinfluence of afluoride mouthwash containing nanohydroxyapatite on the dentin bonding interface microhardness of direct resin composite restorations in situ. Methodology: Forty human premolars were sectioned and restored with a three-step adhesive system or a self-etch adhesive system and a conventional resin-based composite. After the initial microhardness measurements on the samples’ dentin interface, the restored samples were fixed in acrylic palate appliances for an in situ experiment. Ten volunteers participated in a randomized double-blinded crossover study using the palate appliances and a placebo fluoride mouthwash for one week, one-week wash-out, and one-week fluoride mouthwash containing nanohydroxyapatite. The final microhardness measurements were evaluated, and data were analyzed by ANOVA and Tukey’s test submitted for multiple comparisons (α = 0.05; 0.8 power). Results: There were statistically significant differences between the mouthwash treatments with both adhesive systems tested (p < 0.001). The nanohydroxyapatite used in the mouthwash was an influencing actor on the dentin interface microhardness of resin composite restorations. Conclusion: The fluoride mouthwash containing the nanohydroxyapatite was able to increase the dentin microhardness of the direct resin composite restorations regardless of the adhesive system used.

Authors: Dayane Carvalho Ramos Salles de Oliveira, Livia Rodrigues de Menezes, Lúcia Trazzi Prieto, Erick Kamiya Coppini, Luís Alexandre Maffei Sartini Paulillo, Gisele Damiana da Silveira Pereira

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