Art-5-Malamet

PROSTHETIC DENTISTRY                                                                                                                                 www.stomaeduj.com




SELECTING AN APPROPRIATE OCCLUSAL SCHEME WHEN




                                                                                                                                                   Review Articles
FABRICATING IMPLANT-SUPPORTED FIXED DENTAL
PROSTHESES: A SYSTEMATIC REVIEW
Mariam Margvelashvili-Malament1a* , Kenneth Albert Malament1b                       , Steven E. Eckert2c

1Department of Prosthodontics, School of Dental Medicine, Tufts University, Boston, MA, USA
2College of Medicine, Mayo Clinic, Rochester, MN, USA
a
  DMD, MSc, PhD, Assistant Professor; e-mail: mariam.malament@tufts.edu; ORCIDiD: https://orcid.org/0000-0002-3751-0675
b
  DDS, MScD, Clinical Professor; e-mail: kenneth.malament@tufts.edu; ORCIDiD: https://orcid.org/0000-0002-7144-5643
c
 DDS, MS, Professor Emeritus; e-mail: seeckert@me.com; ORCIDiD: https://orcid.org/0000-0001-9382-7135

ABSTRACT                                                                         https://doi.org/10.25241/stomaeduj.2021.8(3).art.5

Background Dental implants are ankylosed in the bone without a periodontal ligament resulting in a lack
of micro-mobility during chewing. Consequently, occlusion with dental implants may be at greater risk,
specifically when the teeth come into contact in lateral excursive movements.
Objective A systematic review of the literature was performed to identify occlusal concepts that were most
favorable for implant-retained fixed restorations.
Data Sources A search of the literature was conducted using PubMed and EndNote literature online software
databases. Keywords were used to assist in the identification of the literature.
Study Selection The literature search identified 49 articles using PubMed and 33 articles using the author-
created EndNote database.
Data Extraction Two occlusal concepts were identified, namely mutually protected occlusion and group
function unilateral occlusion. None of the articles demonstrated clear scientific evidence to identify
superiority of one concept over the other.
Data Synthesis Based upon the systematic review of the literature, no scientific evidence was identified
favoring any specific occlusal concept.

KEYWORDS
Occlusion; Dental Implants; Implant Supported Fixed Restoration; Mutually Protected; Group Function.


1. INTRODUCTION                                                             or they could support the entire dentition with
                                                                            fixed dental prostheses. Although natural teeth and
The primary purpose of teeth is to prepare food for                         dental implants may provide similar support for
ingestion. Processing food demands the actions of                           dental prostheses, there are substantial differences
trituration, manipulation, and deglutition. When                            between the two. The implant is an alloplastic device
teeth are lost, the function is compromised [1]. The                        that replaces the natural tooth root and supports
replacement of missing teeth is accomplished using                          the prosthesis. Although implants may provide
dental prostheses. These prostheses may be used to                          aesthetic and comfortable tooth replacement, there
replace all the teeth with complete dental prostheses,                      are characteristics associated with the use of dental
or some of the teeth with partial dental prostheses.                        implants that must be considered [5]. Perhaps the
Replacement teeth may gain support using remaining                          most obvious is the lack of a periodontal ligament
natural teeth, dental implants, residual alveolar                           around implants and thus a lack of micro-mobility
ridges, or a combination of these structures. Studies                       during chewing. Consequently, occlusion with dental
clearly indicate that removable prostheses are not as                       implants may be at greater risk, especially when teeth
effective in restoring function, esthetics, and patient                     contact in lateral excursions [6].
self-esteem. In fact, multiple nutritional deficiencies,                    The aim of this review was to identify the most har-
associated comorbidities, and loss of self-confidence                       monious relationship of prosthetic teeth when sup-
have been reported with removable prostheses [2-4].                         ported by dental implants and describe occlusal
Implants may provide single tooth replacement,                              theories using a systematic review.

             OPEN ACCESS This is an Open Access article under the CC BY-NC 4.0 license.
             Peer-Reviewed Article
  Citation: Margvelashvili-Malament M, Malament KA, Eckert SE. Selecting an appropriate occlusal scheme when fabricating implant-supported fixed
  dental prostheses: a systematic review. Stoma Edu J. 2021;8(3):189-194.
  Received: July 17, 20211; Revised: August 05, 2021; Accepted: September 03, 2021; Published: September 07, 2021
  *Corresponding author: Dr. Mariam Margvelashvili-Malament, Assistant Professor
  Department of Prosthodontics, School of Dental Medicine, Tufts University, 1 Kneeland Street, Boston MA 02111, USA
  Tel: +1 (617) 636-7000; Fax: +1 (617) 636-6583; e-mail: mariam.malamet@tufts.edu
  Copyright: © 2021 the Editorial Council for the Stomatology Edu Journal.




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                    Margvelashvili-Malament M, et al.
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                    2. MATERIALS AND METHODS
Review Articles                                                                    Database/                   Search terms                 Filters used            Results
                                                                                   Software
                    The research question for this review was formulated                 PubMed             “(dental implants OR        Humans, Randomized            49
                    following the Preferred Reporting Items for Syste-                                    implants) AND Occlusion      Controlled Trial, Clinical
                                                                                                        AND implant restoration AND    Trial, Systematic Review
                    matic Reviews and Meta-Analyses (PRISMA) guide-                                      "dental implants"[Mesh]”
                    lines using the Population, Intervention, Comparison
                                                                                           EndNot          "Dental Occlusion and                                      33
                    and Outcome (PICO) tool.                                                              Dental Implant and Fixed
                    POPULATION: The patient group receiving fixed                                         Prosthesis or Occlusion or
                    dental prostheses supported by implants.                                            Group Function and Mutually
                                                                                                                 Protected”
                    INTERVENTION: The patient group receiving a spe-
                                                                                  Hand search                        N/A                         N/A                  3
                    cific form of treatment. Unilateral group function lat-
                    eral occlusion with multiple posterior teeth guiding         Table 1. Search strategy.
                    lateral movements.
                                                                               2.1. Screening Process
                    COMPARISON: The patient group receiving an alter-          A total of 49 (PubMed) and 33 (EndNote) articles
                    native form of treatment. Mutual protection placing        were selected by two of the authors (M.M.M. and
                    lateral contacts on anterior teeth thereby separating      S.E) as being of potential interest to the reader on
                    the posterior teeth during mandibular movements.           the topic of dental occlusion. These articles were as-
                    OUTCOME: The results obtained from the two com-            sessed by reviewing the titles and then by reading
                    pared treatments.                                          the abstracts. Any disagreement regarding the qual-
                    In partially and/or completely edentulous patients         ity of the article was managed through discussion
                    restored with implant-supported fixed dental               and eventually by the inclusion of the third author
                    prostheses either a mutually protected occlusion,          (K.A.M) if necessary.
                    whereby the anterior teeth separate the posterior          The authors, after compilation and assessment of
                                                                               the articles, extracted the available data from the ar-
                    teeth in laterotrusion, or a group function occlu-
                                                                               ticles and compiled the gathered data. The articles
                    sion, where the anterior and posterior teeth contact
                                                                               were evaluated relative to the use of natural tooth
                    simultaneously on the working side result in fewer         support or dental implant support of the final pros-
                    complications? The dental literature was to be evalu-      theses.
                    ated to determine the relative superiority of one
                    occlusal scheme over the other to answer the PICO          3. RESULTS
                    question.
                    An electronic search was conducted utilizing the           Using the literature search described, no studies
                    following database and Software: PubMed and                were identified to answer the PICO question. There
                    EndNote using the search strategy “(dental implants        were subjective descriptions of different techniques
                    OR implants) AND Occlusion AND implant resto-              that were used in the management of clinical pa-
                    ration AND "dental implants"[Mesh]” and "Dental            tients relative to the posterior fixed occlusal scheme.
                    Occlusion and Dental Implant and Fixed Prosthe-            The PubMed search was linked with 49 articles. After
                                                                               screening the titles, 39 were assessed as irrelevant, 7
                    sis or Occlusion or Group Function and Mutually
                                                                               as potentially relevant, 2 as hypothetical designs and
                    Protected” respectively. No language or journal type
                                                                               1 as relevant. The EndNote search was linked with 33
                    restrictions were applied to the search. A supple-         articles, 23 were reviewed as irrelevant, 7 potentially
                    mental hand search was also conducted. Search              relevant, 3 represented hypothetical designs (Fig. 1).
                    strategy and outcomes for each source are provided
                                                                               Identification




                    in Table 1.                                                                   Records identified through
                    To meet the eligibility requirements, the selected                           database search: PubMed (49),
                                                                                                 EndNote (33), Hand Search (3)          Records excluded after title
                    studies had to meet the following inclusion criteria:                                                                screening: PubMed (39),
                    1. Human studies.                                                                                                         EndNote (23)
                                                                               Screening




                                                                                                 Records remaining after title
                    2. Randomized controlled clinical trials (RCT), clinical                       screening: PubMed (10),
                    trials, systematic reviews.                                                  EndNote (10), Hand Search (3)
                    3. If multiple publications on the same cohort to be                                                                 Duplicate records excluded
                    found, only the publication with the longest follow-                        Records remaining after abstract       Records excluded after abstract
                                                                               Eligibility




                    up time was included.                                                         level screening: PubMed (3),          level screening: PubMed (7),
                                                                                                           EndNote (7)                  EndNote (3), Hand Search (3)
                    The exclusion criteria included the following:
                    1. Not meeting inclusion criteria.
                                                                               Included




                                                                                                   Full-text articles assessed for       Full-text articles excluded:
                    2. Duplicate publications.                                                  eligibility: PubMed (3), EndNote (7)      PubMed (2), EndNote (4)
                    3. Full-text not available in English.
                    4. Full-text unavailable.                                                          Studies included:
                                                                                                    PubMed (1), EndNote (3)
                    5. No information available about occlusal concepts
                    applied.                                                     Figure 1. Screening process.




 190                Stoma Edu J. 2021;8(3):189-194                                                             pISSN 2360-2406; eISSN 2502-0285
Occlusion on fixed implant restorations
                                                                                                                                                                          www.stomaeduj.com



Dental occlusion described as mutually protected                                      occlusal design concept over another. Even from




                                                                                                                                                                        Review Articles
occlusion was identified as the most common                                           the standpoint of descriptive studies there is no
method of management of lateral articulation of the                                   clear recommendation. The lack of a periodontal
teeth. Group function was identified in three articles,                               ligament limits the micromotion and proprioceptive
although no scientific studies were performed. Due                                    capability of implant-supported fixed restorations
to an inability to identify a study, or studies, that                                 making them potentially more succeptible
answer the PICO question or provided conceptual                                       to technical complica-tions. Therefore, it is of
homogeneity, no Meta-Analysis or risk of bias                                         paramount importance to provide optimal occlusion
assessment could be conducted. The following                                          to hopefully generate higher survival rates for
opinion-based and clinical articles were identified                                   implant-supported fixed restorations. However, the
and are summarized in Table 2.                                                        question remains as to what is the optimal occlusal
Wismeijer et al. [7] described implant reconstruction                                 scheme. Although this systematic review failed to
in the edentulous mandibular arch opposing an                                         identify studies that would answer the question
edentulous maxilla as being treated using bilateral                                   directly, suggestions dervied from the included
balanced occlusion. Mutually protected occlusion or                                   articles as well as the factors that may be considered
group function was suggested when the maxilla was                                     confounding variables are further discussed.
dentate. In an article that was primarily describing                                  Two occlusal concepts that are currently applied to
the use of short implants in the posterior areas,                                     fixed restorations on implants are: group function
Misch et al [8] suggested that cantilevers should                                     occlusion and mutually protected occlusion.
be eliminated, and the patient should be restored                                     Both occlusal approaches share the concept of
with a mutually protected or canine guided occlusal                                   simultaneous, bilateral contact of posterior teeth
concept.                                                                              when the jaws are in maximum intercuspation.
In 2016, Sheridan et al. [9] performed a systematic                                   The concepts differ in the way that occlusion of
review that failed to identify evidence in favor of any
                                                                                      the anterior teeth is described with group function
specific occlusal management. Once again, these
                                                                                      exhibiting very light contact of the anterior teeth
authors suggested mutually protected occlusion
                                                                                      while mutual protection entails anterior teeth
with anterior guidance with wide freedom in
                                                                                      contact in all excursive movements thereby
centric and avoidance of cantilevers. Considering
                                                                                      separating the posterior teeth.
the descriptors, specifically with “wide freedom in
                                                                                      Mutually protected occlusion is considered by
centric,” the readers may have interpreted the terms
as fulfilling the description of group function.                                      many to be the ideal occlusal scheme for the
Esquivel-Upshaw et al [10] studied the effect of                                      natural dentition. D’Amico described the size and
direction and magnitude of occlusal loading on                                        innervation of the canine tooth as a way to explain
implant supported FDPs. The authors provided group                                    the rationale for embracing the mutual protection
function to the treated patients and identified these                                 concept [11-13]. Conversely, group function exhibits
lateral excursive contacts as not being associated                                    unilateral, simultaneous anterior and posterior tooth
with a higher fracture occurrence. Conversely, the                                    contact as the jaws move laterally from maximum
strong centric contacts resulted in higher porcelain                                  intercuspation. Primary support for the concept of
fracture rate. None of the treated patients received                                  group function is seen when the dentition exhibits
mutually protected occlusion. The authors suggested                                   abrasive wear after years of function [14-18].
that due to the absence of a periodontal ligament,                                    Although without clear scientific or clinical evidence,
implant supported fixed dental prostheses should                                      three of the selected four studies recommended
have lighter maximum intercuspation contacts.                                         mutually protected occlusion for implant-supported
                                                                                      fixed restorations.
4. DISCUSSION                                                                         Most of the authors highlight the complexity of
                                                                                      biomechanics with implant-supported fixed dental
This systematic review of the literature failed to                                    prostheses. Misch et al. suggested decreasing
identify randomized controlled clinical trials or                                     stress through a biomechanical approach, namely:
cohort studies that would promote one specific                                        splinting implants and avoiding cantilevers, applying
  Author/Year             Journal             Study           Sample Size       Occlusal       Observation        Prostheses’                   Results
                                              Design        (number of FDPs   Concept Used        Time          Survival Rate (%)
 Wismeijer, D. et         Journal of           Review            N/A               N/A             N/A                N/A           Recommends mutually protected
    al 1995          Prosthetic Dentistry                                                                                                    occlusion
   Misch, C. E.          Journal of         Retrospective        338            Mutually       Up to 6 years        N 98.9%         Recommends methods to decrease
   et al 2006          Periodontology        Case Series                        protected                                            biomechanical stress (including
                                                                                                                                      mutually protected occlusion)
 Sheridan, R. A.      Implant Dentistry        Review            N/A               N/A             N/A                N/A           Recommends mutually protected
   et al 2016                                                                                                                                occlusion
Esquivel-Upshaw,     Journal of Dentistry       RCT               89          Group Function     3 years              85%           Recommends light centric contacts
 F. H. et al 20146
 Table 2. Included studies.



Stoma Edu J. 2021;8(3): 189-194                                                                                pISSN 2360-2406; eISSN 2502-0285                          191
                    Margvelashvili-Malament M, et al.
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                    a mutually protected occlusal concept, and selecting     it was made originally will provide a cosmetic
Review Articles     an implant design to increase bone-to-implant            benefit for the patient but in terms of full functional
                    contact area. Unfortunately, this study lacked a         replacement, the incremental stacking of porcelain
                    control group utilizing an alternative occlusal          will never be so accurate that it could be used
                    concept. Mutually protected occlusion resulted in        without adjustment. In addition to the abrasive
                    high survival rates, yet the study does not answer       nature of metal ceramic restorations there is also a
                    the PICO question of current systematic review. It       tendency for the material to lose surface detail over
                    shows successful application of this occlusal concept    time. The cost of metal ceramic is dependent upon
                    but fails to demonstrate its superiority [8].            the type of metal alloy that is used. This is a material
                    Esquivel-Upshaw, et al. showed no risk of higher         that was quite popular through the first decades of
                    fracture of implant-supported fixed dental prosthesis    implant dentistry but it appears to have lost much of
                    in excursive contacts (group function). This was         the previous popularity of this material.
                    true for both metal-ceramic and ceramic-ceramic          The use of milled, or pressed, all ceramic materials
                    restorations. However, similarly to Misch there          has demonstrated a number of advantages. Since
                    was no control group of the alternative occlusal         the design of such a prosthesis (milled) can be
                    concept group. Regardless, the authors recommend         saved digitally, any future damage in the form of
                    hypoocclusion in maximum intercuspation on               breakage, could be easily restored as long as the
                    implant-supported fixed restorations [10].               fixed dental prosthesis is retrievable. Perhaps a more
                    Another concept that should be mentioned is              important advantage is that monolithic all ceramic
                    bilateral balanced occlusion. Unlike mutually pro-       materials exhibit very little, if any, discernible wear
                    tected occlusion and group function, bilateral           over time. With the advent of lithium disilicate
                    balance provides bilateral contacts in eccentric         and zirconia materials the aesthetic replacement
                    movements. While this occlusal concept is popular        of posterior teeth should be easy to achieve and
                    in complete denture prosthodontics, it should            reliable and predictable into the future. Assuming
                    also be considered when a fixed restoration              that the choice of material will be that of a milled
                    opposes a removable complete denture. When a             all ceramic material, it is important to remember
                    prosthodontist considers the alternative occlusal        the unique characteristics of the dental implant
                    concepts for treating edentulous pateints with fixed     that must be duplicated or compensated for in the
                    prostheses, the decision is often made based upon
                                                                             final prosthesis. Perhaps the most critical factor as it
                    clincal experience and personal and laboratory
                                                                             relates to implants is the relative immobility of the
                    preferences. However, another important aspect
                                                                             individual implants. Unlike natural teeth that exhibit
                    that should be considered is the type of restorative
                                                                             physiologic mobility, implants are, for all intents and
                    material being used. Normally the material choices
                                                                             purposes, rigid within bone. This rigid device must
                    are acrylic resin, cast metal, metal-ceramic, and
                                                                             have a carefully controlled occlusal relationship
                    milled or pressed ceramic materials. Over time,
                                                                             with the opposing teeth. The patient can advise the
                    the use of acrylic resin has diminished because of
                    unfavorable wear characteristics. Although acrylic       clinician of the presence of high occlusal contacts
                    resin prostheses usually have a supporting metal         but it is very hard to communicate to the patient the
                    substructure, the wear characteristics of acrylic        more important factor related to lateral motions and
                    or composite materials as an occlusal material           how those must be compensated in the prosthetic
                    demonstrate moderate to severe wear in a relatively      design.
                    short period of time. The prostheses can be removed
                    and the surface veneering material replaced, but         5. CONCLUSIONS
                    this will require a number of appointments that
                    will incur some cost. In addition, the customization     Within the limitations of this systematic review the
                    of the occlusal surface of the prosthesis may create     authors agreed on the following conclusions:
                    an occlusal awareness for the patient that could be      • There is lack of information as to which occlusal
                    unfavorable.                                             scheme, mutually protected or group function, is
                    Full cast metal restorations could certainly be          more favorable.
                    considered. The advantage of cast metal is that          • Based upon clinical preference and experience,
                    most cast materials exhibit a hardness and a wear        group function or mutually protected occlusion,
                    pattern similar to that seen with natural dentition.     both appear to be acceptable occlusal schemes for
                    The disadvantage of cast metal is the appearance         implant supported fixed dental prostheses.
                    and the relatively high cost associated with such a      • Future clinical studies are needed to assess
                    prostheses. In today's esthetically conscious society,   scientific and clinical evidence of the superiority of
                    full cast metal restorations are unlikely to prove       one occlusal scheme over other.
                    acceptable. Metal ceramic restorations have been
                    one of the most popular choices for restorative          AUTHOR CONTRIBUTIONS
                    material for more than 50 years. Metal ceramic is        MM-M: was responsible for the conceptualization, design, data
                    relatively stable over time although it is somewhat      analyses and writing the manuscript. SE: was responsible for the
                    prone to chipping and fracture of the veneering          conceptualization, design, and data analyses, and editing the
                    ceramic material. The restoration, because of the        manuscript. KM: was responsible for editing the manuscript. All
                    fabrication process, is built up incrementally. The      the authors gave their final approval and agreed to be accountable
                    ability to duplicate a prosthesis sometime after         for all aspects of the work.




 192                Stoma Edu J. 2021;8(3):189-194                                             pISSN 2360-2406; eISSN 2502-0285
Occlusion on fixed implant restorations
                                                                                                                                               www.stomaeduj.com



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                                                        Mariam MARGVELASHVILI-MALAMENT
                                                                             DMD, MSc, PhD, Assistant Professor
                                                                                Department of Prosthodontics
                                                                                    School of Dental Medicine
                                                                                     Tufts University - TUSDM
CV                                                                                            Boston, MA, USA
Dr. Margvelashvili-Malament is an Assistant Professor in the Department of Prosthodontics at Tufts University School of
Dental Medicine (TUSDM). She is a Diplomate of the American Board of Prosthodontics and Fellow of the American College of
Prosthodontics.
She received her DMD from the Tbilisi State University in Georgia, Master of Science and PhD Degrees in Dental Materials from
the University of Siena, Italy. She is a co-author of the national residency program in Prosthodontics in Georgia. She was also the
Founding Chair of the International Dental Program at the University of Georgia.
She is the recipient of an ITI Scholarship. She completed her Advanced Graduate training in Prosthodontics at TUSDM with
high honors. She has lectured internationally and published numerous scientific articles and she also serves as a reviewer for
international journals.




Stoma Edu J. 2021;8(3):189-194                                                           pISSN 2360-2406; eISSN 2502-0285                     193
                    Margvelashvili-Malament M, et al.
www.stomaeduj.com




                    Questions
Review Article
                    1. How can mutually protected occlusal concept be described?
                    qa. An occlusal scheme in which the posterior teeth prevent excessive contact of the anterior teeth in
                    maximal intercuspal position, and anterior teeth disengage the posterior teeth in all mandibular excursive
                    movements;
                    qb. An occlusal scheme in which multiple posterior teeth contact in all mandibular excursive movements
                    on the working side to distribute occlusal forces;
                    qc. An occlusal scheme in which the buccal and lingual cusps of the maxillary posterior teeth on working
                    and balancing side contact buccal and lingual cusps of mandibular posterior teeth in all mandibular
                    excursive movements;
                    qd. None of the above.
                    2. How can group function occlusal concept be described?
                    qa. An occlusal scheme in which the posterior teeth prevent excessive contact of the anterior teeth in
                    maximal intercuspal position, and anterior teeth disengage the posterior teeth in all mandibular excursive
                    movements;
                    qb. An occlusal scheme in which multiple posterior teeth contact in all mandibular excursive movements
                    on the working side to distribute occlusal forces;
                    qc. An occlusal scheme in which the buccal and lingual cusps of the maxillary posterior teeth on working
                    and balancing side contact buccal and lingual cusps of mandibular posterior teeth in all mandibular
                    excursive movements;
                    qd. None of the above.
                    3. Slightly hypo-occlusion in maximal intercuspal contacts is recommended for
                    implant-supported fixed restorations because:
                    qa. The lack of a periodontal ligament limits the micromotion;
                    qb. The lack of a proprioceptive capability of implant-supported fixed restorations;
                    qc. Both a. and b. are correct;
                    qd. None of the above.
                    4. Based on the findings of this systematic review, the following is correct:
                    qa. There is a lack of information as to which occlusal scheme, mutually protected or group function, is
                    more favorable for implant-supported fixed restorations. Group function or mutually protected occlusion,
                    both appear to be acceptable occlusal schemes;
                    qb. There is strong scientific evidence that suggests the use of group function occlusal concept for
                    implant-supported fixed restorations;
                    qc. There is strong scientific evidence that suggests the use of mutually protected occlusal concept for
                    implant-supported fixed restorations;
                    qd. None of the above.




 194                Stoma Edu J. 2021;8(3): 189-194                                       pISSN 2360-2406; eISSN 2502-0285