articol3_2021_nr2

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                    ORTHODONTICS
                    CONE BEAM TOMOGRAPHY AND PANORAMIC
Original Articles
                    RADIOGRAPHY IN LOCALIZATION OF IMPACTED
                    MAXILLARY CANINE AND DETECTION OF ROOT
                    RESORPTION
                    Seden Akan1a* , Husamettin Oktay2b
                    1
                        Department of Orthodontics, Faculty of Dentistry, Altınbaș University, Bakırköy / İstanbul, Turkey
                    2
                        Department of Orthodontics, İstanbul Medipol University Faculty of Dentistry, İstanbul, Turkey

                    DDS, PhD, Assistant Professor; e-mail: sedenakandt@hotmail.com; ORCIDiD: https://orcid.org/0000-0001-7955-3086
                    a

                    DDS, PhD, Professor; e-mail: hoktay@medipol.edu.tr; ORCIDiD: https://orcid.org/0000-0001-7862-2983
                    b


                    ABSTRACT                                                                                https://doi.org/10.25241/stomaeduj.2021.8(2).art.3

                    Introduction The aim of this study was to evaluate cases of impacted maxillary canines (IMC) using cone
                    beam tomography (CBCT) and panoramic images in an attempt to assess if panoramic radiographs can
                    provide information compatible with CBCT results regarding canine position and root resorption.
                    Methodology Fifty-six impacted maxillary canines from 48 patients were radiographically evaluated. The
                    positions of the canine teeth were classified by Sector localization on panoramic radiographs and the same
                    teeth were also analyzed by KPG on CBCT. Root resorptions in maxillary lateral incisors were also evaluated
                    on CBCT. The relationships between panoramic and CBCT findings were compared by Chi-square test and
                    Fischer’s exact test.
                    Results Statistically significant correlations were found between panoramic Sectors and KPG indexes
                    (p<0.001). KPG index values of 1, 3 and 4 corresponded to the panoramic Sectors 1, 4 and 5, respectively;
                    but KPG index 2 matched the panoramic Sectors 3 and more often 2. Mid-alveolar impaction generally
                    coincided with score 1 for both KPG index and panoramic Sector. In palatally IMC, this score value was
                    generally 2 or 3 for the KPG index and 4 for the panoramic Sector (p≤0.001). Root resorptions in maxillary
                    lateral incisors showed significant differences according to Sector localization and KPG index (p<0.05),
                    namely they coincided with 2 and 3 in Sector evaluation and 2, 3 and 4 in KPG index.
                    Conclusions Sector location on OPG is found to be related to KPG index on CBCT, and it can help evaluate
                    mainly certain positions of impacted canines; thus, unnecessary CBCT scans are not requested.
                    KEYWORDS
                    Impacted Canine; KPG Index; Radiography Dental; Digital Radiography Panoramic; Sector Classification.

                    1. INTRODUCTION                                                                     The determination of impacted canine positions
                                                                                                        is critical for the planning of orthodontic-surgical
                    Maxillary canines play important roles in facial                                    treatment. The panoramic radiographic evaluation
                    esthetics, dental arch development, and oral                                        is the most common clinical approach used by or-
                    cavity functions. Non-erupted maxillary canines are                                 thodontists for this procedure. It should be known,
                    relatively common because these teeth develop                                       however, that panoramic radiographs have some
                    deep within the maxilla and follow a longer path                                    limitations in evaluating the labiopalatal positions
                    to erupt into the oral cavity when compared to                                      of impacted canines [5]. In addition, it is difficult
                    other teeth [1]. An impacted tooth can be defined                                   to localize and determine the root resorptions of
                    as the tooth that has failed to erupt into the proper                               adjacent teeth with this radiographic method
                    position in the dental arch within the normal                                       because of the superimposition of the related
                    period of growth, and maxillary canines are the most                                structures, leading to a difficulty in distinguishing
                    common teeth suffering from impaction except                                        many significant details [6].
                    third molars. The prevalence of their impaction ran-                                Many studies have been carried out to overcome these
                    ges from 1% to 3% in the general population [2-4].                                  shortcomings regarding panoramic radiographic

                                    OPEN ACCESS This is an Open Access article under the CC BY-NC 4.0 license.
                                    Peer-Reviewed Article
                         Citation: Akan S, Oktay H. Cone beam tomography and panoramic radiography in localization of impacted maxillary canine and detection of root
                         resorption.Stoma Edu J. 2021;8(2):106-112.
                         Received: December 18, 2020; Revised: January 10, 2021; Accepted: January 21, 2021; Published: January 25, 2021
                         *Corresponding author: Dr. Seden Akan; Altınbaş Üniversitesi Diş Hekimliği Fakültesi Zuhuratbaba Mahallesi, İncirli Caddesi, No:11-A 34147 Bakırköy,
                         İstanbul, Turkey.
                         Tel/Fax: 0090535 5113760; e-mail: sedenakandt@hotmail.com
                         Copyright: © 2021 the Editorial Council for the Stomatology Edu Journal.




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Akan S, et al.
                                                                                                                                                         www.stomaeduj.com




                                                                                                                                                       Original Articles
 Figure 1. Modified Sector classification according to the mesiodistal    Figure 2. KPG index is calculated by summing the scores (0 to 5 scores) of
position of the canine cusp tip on OPG.                                  the canine cusp tip and root tip on x, y and z planes.

evaluations [7-11]. One of them belonged to Ericson                      was seen in 8 patients, while 40 of them had unilater-
and Kurol [8] who proposed some measurements on                          al impaction. After a routine panoramic radiograph-
panoramic radiographs to predict the possible im-                        ic evaluation, CBCT scans were needed in order to
paction of maxillary canines in relation to the adja-                    obtain more detailed information on the impacted
cent lateral incisors.                                                   canines for button operation. Panoramic records
Their sector classification was then modified by
                                                                         (OPG) were obtained by Carestream (Kodak) OPG
Leonardi et al [12] and Bacetti et al [13] and gained
                                                                         Dental Machine (Carestream, Canada). CBCT scans
popularity among the orthodontists and dental
radiologists [14,15].                                                    were taken by I-CAT Next Generation & i-Cat VisionQ
Cone-beam computed tomography (CBCT) used for                            machine, (Imaging Sciences International, LLC,
three-dimensional visualization has gained more                          Hatfield, PA) at a setting of 120 kVp and 3.7 m.
popularity in dental clinics during the last 3 de-                       Both the OPG records and CBCT images of the 56
cades [16] and at present, it has been accepted as                       impacted canines were analyzed. The mesiodistal
the most accurate method in impacted tooth local-                        positions of the canine crowns were determined
ization [17] although CBCT gives more radiation to                       on panoramic radiographs and classified by the
the patients than conventional radiographs. In order                     Sector classification method, which was modified by
to develop evidence-based guidelines on the use of
                                                                         Leonardi et al [12] and Bacetti et al [13] (Fig. 1).
CBCT in dental and maxillofacial imaging, a project
                                                                         The KPG index, a novel index based on 3D CBCT
named SEDENTEXCT was accomplished between
2008-2011 in Europe [17]. According to this project,                     images, was calculated by summing the scores
CBCT records may be indicated only in cases where                        (0 to 5 scores) of the canine cusp tip and root tip
inadequate information is obtained from conven-                          on x, y and z planes (Fig. 2). The total KPG scores
tional radiographs about impacted canines and their                      between 0 and 9 were classified as follows: 10 as
localizations.                                                           easy, 14 as moderate, 15 and 19 as difficult and 20
CBCT presents a reliable guidance of the used                            and above as extremely difficult. These categories
mechanics, force, and treatment style to move the                        were named as 1, 2, 3, and 4 beginning from the easy
impacted canines efficiently with lower complica-                        group in order to make the comparison with the
tions. To standardize the classification of impacted                     Sector groups easy. The root resorptions of adjacent
maxillary canines and to predict treatment difficulty,
                                                                         maxillary lateral incisors and labiopalatal positions
KPG index was introduced by Kau et al [18] in 2009.
                                                                         of the impacted canines were also evaluated on
The aims of the present study were to investigate if
the panoramic radiographs can provide information                        CBCT. The labiopalatal positions of the impacted
related with CBCT results regarding canine position                      canines were classified as labial, mid-alveolar, and
and root resorption.                                                     palatal. Root resorptions were settled as yes or no.
                                                                         The labiopalatal positions of the impacted canines
2. SUBJECTS AND METHODS                                                  and resorptions at lateral incisors were correlated
                                                                         with the KPG indexes and Sector classifications.
This retrospective radiographic study, being appro-                      Panoramic and CBCT images were scored twice by
ved by the institutional ethical board (108400987-                       one author (S.A.) at a two-week interval. Intraobserv-
97-86), was carried out on the diagnostic records of
                                                                         er reliability was assessed by Kappa coefficient.
48 patients applied at the Orthodontic Department
                                                                         The relationships between panoramic and CBCT
of the Dental School at Istanbul Medipol University;
the patients complained of maxillary canine impac-                       findings were investigated by Chi-square and Fish-
tion. The age of the subjects ranged between 12-34                       er’s exact tests. The data analysis was performed
and the mean age was 18.31±4.99 years. The patients                      using SPSS 16.0 software package (SPSS Inc.,
having any syndrome, tooth aplasia, or undeveloped                       Chicago, IL, USA). P values lower than 0.05 were ac-
canine root were excluded. Bilateral canine impaction                    cepted as statistically significant.


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                    CBCT and panoramic radiography in impacted canines
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Original Articles    Table 1. Relationships between Sector classification and KPG index.

                                                                                                Sector Classification
                           KPG Index
                                                         1                   2                    3                  4                5                Total
                                 1                      11                   0                    0                  2                0                 13
                                 2                       1                  10                    9                  5                0                 25
                                 3                       1                   1                    5                  8                1                 16
                                 4                       0                   0                    0                  0                2                  2
                               Total                    13                  11                   14                  15               3                 56
                    p<0.001


                     Table 2. Relationships among KPG index, Sector classification and CBCT findings.

                                                                                            KPG Index                              Sector Classification

                                                                                 1    2     3     4        Total          1    2      3     4     5          Total

                           Lateral incisor
                              contact                        No contact          12   6     6      2         26           12   2      2     8     2           26

                                                              Contact            1    19   10      0         30           1    9     12     7     1           30

                                                         No resorption           13   11    8      2         34           13   4      6     9     2           34
                           Lateral incisor
                           root resorption                   Resorption          0    14    8      0         22           0    7      8     6     1           22

                                                              Bukkal             2    3     5      0         10           3    0      6     1     0           10

                              Labiopalatal                Mid-alveolar           9    4     0      0         13           9    4      0     0     0           13
                                position
                                                              Palatal            2    18   11      2         33           1    7      8    14     3           33
                    Root resorption of the maxillary lateral incisors was found more in score 2 of the KPG index (p=0.004) and in score 3 of the Sector classification
                    (p=0.011). The indicative scores were 2 or 3 in KPG index and; 2, 3 and 4 in panoramic Sectors for palatally impacted canines (p≤0.001).

                    3. RESULTS                                                                  tions in adjacent teeth, to schedule ortho-surgical
                                                                                                procedures, and to give an opinion about orthodon-
                    Kappa coefficients showing intraobserver reliability                        tic treatment time. It has been stated that one of
                    were high for both panoramic and CBCT images:                               the major reasons for treatment failure of impacted
                    0.748 for lateral incisor root resorption and 0.858 for                     canines is mistaken location anddirectional of trac-
                    labiopalatal position of the impacted canine. Table I                       tion (40.5%) [19]. The main objectives of the present
                    shows a statistically significant association between
                                                                                                study were to assess therelation between 2D and
                    Sector classification and KPG index (p<0.001). KPG
                                                                                                3D visualization of impacted maxillary canines, to
                    indexes 1, 3, and 4 corresponded to panoramic Sec-
                    tors 1, 4, and 5, respectively, while KPG index 2 related                   estimate abiopalatal positions of impacted canines
                    to panoramic Sectors 2 and 3. The results regarding                         from panoramic radiographs, which were routinely
                    the labiopalatal positions of the impacted canines                          used in orthodontic clinics, and to evaluate root
                    and resorptions at the lateral incisors are shown                           resorptions in lateral incisors by CBCT. CBCT is the
                    in Table II. As can be seen from these tables, mid-                         bestcontemporary method to diagnose and localize
                    alveolar impaction generally coincided with score 1                         the impacted canines and their possible complica-
                    in both KPG and Sector evaluations. The indicative                          tions [6,20,21]. It has excellent image quality and
                    scores were 2 or 3 in the KPG index and; 2, 3 and 4                         high diagnostic accuracy for many tasks, such as the
                    in panoramic Sectors for palatally impacted canines                         detection of bone defects, implant treatment
                    (p≤0.001). In labially impacted canines, the indicative                     planning, impacted third molar and canine teeth,
                    score was 3 for both KPG index and the panoramic                            and root re sorption evaluation.
                    sector. The root resorption of maxillary lateral incisors                   In the present study, KPG index values obtained
                    showed significant differences according to Sector
                                                                                                according to CBCT were gathered in more localized
                    localization and KPG index (p<0.05). Resorption was
                                                                                                categories than Sector classification made according
                    found more in scores 2 and 3 in both KPG and Sector
                    evaluations.                                                                to Panoramic radiograph. For example, while lateral
                                                                                                tooth contact and root resorption appear only at 2
                    4. DISCUSSION                                                               and 3 in the KPG index, they are evaluated in almost
                                                                                                all classes in the Sector classification. This result may
                    The determination of impacted maxillary canine                              suggest once again that the diagnostic capability of
                    positions is very important to prevent root resorp-                         the CBCT may be clearer.



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                                                                                                                        www.stomaeduj.com



According to the radiation dose which is the              Sector location on OPG. Olive [29] stated that there




                                                                                                                      Original Articles
main disadvantage of the CBCT, although the               was a significant relationship between the mesiodis-
CBCT exposure dose is relatively low compared             tal position of impacted canines and the treatment
with that of conventional CT, it is up to 10 times        time. Canines impacted in Sector 4 emerged after 21
higher than that of intraoral and extraoral radi-         months of treatment and canines in Sectors 2 and 3
ography used in dentistry [22,23]. To give a more         emerged after 8 months of treatment.
practical example, it has been revealed that the          In literature, there are studies [21,28,30-34] compa-
average effective radiation dose of panoramic             ring the localization of impacted canine by means
radiography is relatively lower, ranging from 4.1 to      of 2D and 3D indexes. Sosars et al [30] evaluated
36 μSv (2-3 days of natural background radiation          106 palatally displaced maxillary canines and they
level), whereas that of CBCT ranges from 19 to 368        concluded that panoramic measurements were
μSv (11 days of natural background radiation level)       not reliable predictors of resorptions, except for
[24, 25]. Thus, a reason for an examination and opti-     severe resorptions, of the neighbor teeth. Khan
mization of this radiographic technique are strongly      Mohammed et al [31] stated that CBCT showed
needed [26]. It is accepted that CBCT scans should        an increased accuracy of 31% compared to
only be requested when there is a potential for CBCT      Panoramic radiography in localizing impacted
images to provide new information not provided by         maxillary canines. Haney et al [32] compared
conventional radiograph [17]. The cases in which          the differences between 2 imaging modali-
diagnosis of impacted teeth is made in initial            ties regarding diagnosis and treatment planning
conventional orthodontic records, CBCT might be           ofimpacted maxillary canines. Two and three di-
requested as a compliment [17]. Should that be the        mensional images of 25 impacted canines were
case, CBCT scan protocols should include a partial        evaluated by 7 of their faculty members, and
field of view comprising the maxilla or the mandible,     significant disagreement was observed among
only. In the light of this information, the present       the evaluators. As a result, they concluded that
study attends to define a correlation between 2D          three-dimensional volumetric imaging might
and 3D qualitative analyses, at least when unnece-
                                                          provide more accurate information for diagno-
ssary CBCT scans are not requested.
                                                          sis and treatment plans. In a similar study carried
The KPG index, introduced in 2009, presents an
                                                          out by Alqerban et al [21], OPG and CBCT images
opportunity to localize the impacted canines us-
                                                          were obtained from 60 consecutive patients who
ing CBCT. Kau et al [27] carried out a study in 2013
                                                          had impacted or ectopically erupting maxillary
to determine the level of agreement of orthodon-
                                                          canines, and these images were analyzed by 11
tists in the management of impacted maxillary
                                                          examiners. The results of that study showed
canines, and found that the KPG index showed a good
                                                          that CBCT was more sensitive than conventional
level of agreement with the clinician’s perception of
                                                          radiography for both canine localization and
difficulty. Dalessandri et al [28] investigated the
agreement between OPG based 2D measurements               identification of root resorption of adjacent teeth.
and the KPG index on 105 impacted maxillary               Altough recent studies have shown that CBCT is
canines. These authors stated that KPG index had          the most sensitive and reliable technique in the
higher intra- and interrater agreement than those         evaluation of craniofacial structures, as stated
of the 2D index, and that yhe KPG index allows            previously, it gives higher radiation doses to the
clinicians to exactly evaluate the position of            patients than the conventional radiographs, thus
impacted canines [28]. As for panoramic radiograph,       it has not come into use routinely in orthodontic
OPG has been accepted as a standard record in             clinics [33]. For this reason, it was necessary to detect
orthodontics. In addition to the clinical examina-        possible relationships between Sector classification
tion of the palatal lump, radiographic evaluation is      on OPG and 3D KPG index. If a strong relationship
generally needed to identify the positions of             is detected between them, OPG can be used safely
impacted canines. With a low radiation dose, OPG          in impacted canine cases. The results of the present
provides an overview of all dentoskeletal structures,     study showed that KPG indexes 1, 3, and 4 mostly
but several factors, such as superimposition of the       matched panoramic Sectors 1, 4, and 5, respective-
structures and inadequate visualization of anterior       ly, and that KPG index 2 matched Sector 2 and 3.
maxilla in horizontal and vertical planes, affect the     According to these results, it could be said that the
image quality of the panoramic radiograph. Sector         Sector analysis is largely compatible with the KPG
classification, carried out on OPG, is a very important   index.
diagnostic tool used in the evaluation of impact-         The accurate diagnosis of exact canine position, po-
ed canines [10,13,29]. Jung et al [15] showed that        tential contacts, and root resorptions of the adjacent
labially impacted canines were frequently in              teeth may reduce complications during treatment.
Panoramic Sectors 1, 2, and 3, mid-alveolus impacted      Jung et al [15] found root resorption in the adjacent
canines in Sector 4, and palatally impacted canines in    teeth only in Sectors 3, 4, and 5. Ericson and Kurol [8]
Sector 5. According to these authors, the labiopalatal    stated that canines in the Sectors 3, 4, and 5 com-
positions of impacted canines can be predicted by         prised 65% of the related root resorptions.


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                    CBCT and panoramic radiography in impacted canines
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                    In the present study, all of the root resorptions                      • KPG indexes 1, 3, and 4 corresponded to panoramic
Original Articles   were in Sectors 2, 3, and 4 and in KPG index 2 and                     Sectors 1, 4, and 5, respectively, while KPG index 2 is
                    3. There was no resorption case in Sector 5. As                        related to panoramic Sectors 2 and 3,
                    can be seen from Table 1, only 3 teeth of 56 im-                       • Lateral incisor root resorption was seen predomi-
                    pacted canine teeth were in sector 5, and 2 of                         nantly in KPG index 2 and 3, and in Sectors 2, 3, and 4.
                    them matched KPG index 4. This means that the                          • Score 1 and 2 for both KPG index and Sector cla-
                    canines in Sector 5 have a deep localization. But it                   ssification showed mid-alveolar impaction; score
                    should not be passed on without being told; these                      3 showed labial impaction for both evaluation
                    are a rather small numbers for drawing reliable                        groups; and score 2 and 3 in KPG index and 2, 3, and
                    conclusions about these scores. This fact may
                                                                                           4 in Sector classification were related to palatally
                    explain the difference between the results of the
                                                                                           impacted canines.
                    present study and those of Jung et al [15] and
                    Ericson and Kurol [8]. These results showed that                       • OPG could help the evaluation of impactedmaxi-
                    the Sector classification of the impacted canines                      llary canine cases by providing information related
                    may help to detect root resorptions at the adjacent                    to CBCT results.
                    teeth. If Sector evaluation on OPG is 2 or above,
                                                                                           CONFLICT OF INTEREST
                    root resorption may have been at the adjacent
                                                                                           The authors declare no conflict of interest.
                    lateral incisors, and thus CBCT evaluation should
                    be recommended for detailed examination. The
                                                                                           ACKNOWLEDGMENTS
                    determination of the labiopalatal positions of the
                    canine cusp tips was an important issue in the                         None
                    diagnosis and treatment planning of impacted
                    canine cases. This evaluation can be made by                           FUNDING
                    Sector classification on OPG or KPG index on                           The authors declare that they have not received any funding.
                    CBCT [10,15]. Jung et al [15] evaluated 73 im-
                    pacted maxillary canines of 63 patients by OPG
                                                                                           COMPETING INTERESTS
                    and CBCT, and classified them by sector location.
                                                                                           The authors declare that they have no competing interests and
                    According to their results, 26 out of the 30 labially
                    impacted canines were located in Sectors 1, 2, and                     revised the article critically. All authors read and approved the
                    3, while 15 out of the 23 mid-alveolus impacted                        final manuscript.
                    canines and 17 out of the 20 palatally impacted
                    canines were in Sectors 4 and 5. In the present study,                 ETHICS APPROVAL AND CONSENT TO PARTICIPATE
                    roughly half of the labially impacted canines had 3                    Written informed consent containing all the information about
                    KPG and Sector scores. All mid-alveolar impacted
                                                                                           records and usage for study was obtained from all patients. All
                    canines had scores 1 and 2 in both KPG index and
                    Sector classification. Of the 33 palatally impacted                    procedures in this study were approved by the Ethical Board of
                    canines, 29 teeth were in the KPG index 2 and 3 and                    the Istanbul Medipol University (108400987-97-86) and com-
                    in Sectors 2, 3, and 4. These results suggest that                     plied with the Code of Ethics of the World Medical Association
                    sector location on OPG could help to predict the                       (Declaration of Helsinki).
                    labiopalatal positions of the impacted canines as it is
                    done by KPG index on CBCT.                                             AUTHOR CONTRIBUTIONS
                                                                                           SA: contributed to the concept and design of the study, to the
                    5. CONCLUSIONS
                                                                                           acquisition, analysis and interpretation of the data and drafting
                    The results of the present study can be summarized                     the article. HO: participated by critically revising the article. All
                    as follows:                                                            authors read and approved the final manuscript.

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Akan S, et al.
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Stoma Edu J. 2021;8(2): 106-112                                                        pISSN 2360-2406; eISSN 2502-0285                      111
                     CBCT and panoramic radiography in impacted canines
www.stomaeduj.com


 Original Articles                                                                                         Seden AKAN
                                                                                               Department of Orthodontics
                                                                                                       Faculty of Dentistry
                                                                                                        Altınbaș University
                                                                                                 Bakırköy / İstanbul, Turkey



                     CV
                     Seden Akan graduated from the Hacettepe University, Faculty of Dentistry, Ankara, Turkey in 2003. She enrolled on her PhD
                     degree in 2004 and she was awarded her PhD degree by the Hacettepe University in 2010. Since 2018, she has been working as
                     an assistant professor at the Department of Orthodontics within the Faculty of Dentistry of the Altınbaș University.




                     Questions
                     1. Which is the most common clinical approach used by orthodontists to determine the
                     impacted canine position?
                     qa. Panoramic radiography;
                     qb. CBCT;
                     qc. Periapical radiography;
                     qd. Bite wing radiography.

                     2. According to the SEDENTEXT Project, in which cases it is indicated to have a CBCT
                     records?
                     qa. In every impacted canine patient;
                     qb. In case inadequate information is obtained from conventional radiographs about impacted canines;
                     qc. Only adult patients with impacted canine;
                     qd. Answers a-d are correct.

                     3. The aim of the present study to evaluate?
                     qa. The efficiency of the CBCT to determine the impacted canine position;
                     qb. The efficiency of the Panoramic radiographs to determine the impacted canine position;
                     qc. The capacity of the impacted canine to resorb the root of the lateral tooth;
                     qd. Thecorrelation between effectiveness of KPG index and sector classification.

                     4. According to the present study results, in which common regions was the lateral tooth
                     root resorption found in the KPG and Sector analysis?
                     qa. 1;
                     qb. 2 and 3;
                     qc. 4;
                     qd. 1 and 2.




 112                 Stoma Edu J. 2021;8(2):106-112                                                 pISSN 2360-2406; eISSN 2502-0285