Art-5_Pani

PROSTHETIC DENTISTRY                                                                                                                                 www.stomaeduj.com




CONVENTIONAL VS SIMPLIFIED COMPLETE DENTURES




                                                                                                                                                   Review Articles
Eleftheria Pani1a* , Aspasia Sarafianou1b , Aspasia Chalazoniti1c , Ioli Ioanna Artopoulou1d , Gregory Polyzois1e

Department of Prosthodontics, School of Dentistry, National and Kapodistrian University of Athens, Athens, Greece
1



a
  DDS, MSc; e-mail: elpani@dent.uoa.gr; ORCIDiD: https://orcid.org/0000-0003-1046-9470
b
  DDS, MSc, Dr. Dent, Assistant Professor; e-mail: sarafia@otenet.gr; ORCIDiD: https://orcid.org/0000-0003-4826-2678
c
 DDS, Postgraduate Student in Prosthodontics; e-mail: ahal@dhal.com; ORCIDiD: https://orcid.org/0000-0002-9833-1494
d
  DDS,MSc, Dr.Dent; e-mail: iartopoulou@gmail.com; ORCIDiD: https://orcid.org/0000-0003-1711-3143
e
  DDS, MScD, Dr. Dent, Professor, Head of Department; e-mail: grepolyz@dent.uoa.gr; ORCIDiD: https://orcid.org/0000-0003-0828-3423

ABSTRACT                                                                                https://doi.org/10.25241/stomaeduj.2021.8(4).art.5

Background Complete dentures are fabricated with the conventional protocol which requires two impressions
-preliminary, final-, the recording of maxillomandibular relationships, two try-ins, and the delivery of the denture.
The final impression is challenging, demanding, and time-consuming. Therefore, simplified methods with the
omission of the final impression have been proposed.
Objective The aim of this systematic review is to compare the conventional with the simplified method according
to masticatory performance and ability, patient satisfaction, oral health related quality of life (OHRQoL), denture
quality, time, and cost.
Data sources An electronic search of the MEDLINE-PubMed, Scopus and Europe PMC databases was conducted
by two researchers.
Study selection Randomized clinical trials, cohort clinical studies and clinical studies of complete dentures
fabricated with the conventional or the simplified method were selected. Patients in need of a complete denture
(Participants/Population) were divided in two categories, those who were treated with the simplified technique
(Intervention) and those who were treated with the conventional technique (Comparison).
Data extraction Between these two categories various outcomes were examined: masticatory performance and
ability, patient satisfaction, OHRQoL, denture quality, time, and cost.
Data synthesis 19 articles fulfilled the inclusion criteria. Moreover, two systematic reviews and one meta-analysis
of the same topic were included. Cost and time differed significantly between the two methods favoring the
simplified protocol.

KEYWORDS
Conventional Complete Dentures; Simplified Complete Dentures; Patient Satisfaction; Clinical Outcomes; Oral
Health Related Quality of Life (OHRQoL)

1. INTRODUCTION                                                                   They reconstruct all the missing hard and soft tissues.
Edentulism is the state of having lost all of the                                 The standard protocol for fabricating a complete
natural teeth and increases following the ageing                                  denture requires six clinical sessions followed by
of the population. According to the systematic                                    five laboratory stages. The clinical sessions include
review and meta-analysis of Roberto et al. [1], the                               preliminary and final impression, maxillomandibular
prevalence of edentulism increases with age and in                                records, try-in of the dentures with the anterior teeth,
the elderly people this is influenced by demographic                              try-in with all the teeth, and finally delivery of the
and socioeconomic factors. All this indicate the                                  complete denture. The preliminary impression is made
multifactorial etiology of edentulism [1].                                        with alginate on a stock tray or with compound on a
Implant therapy is well documented and can provide                                metal tray. The purpose of this impression is to create
a long term and efficient treatment for tooth loss.                               a cast which will be used to fabricate a custom tray.
However, it is not always possible to proceed with                                This custom tray combined with a variety of materials
implant rehabilitation for the edentulous patients due                            will reassure the most detailed impression. This clinical
to medication, risks, cost and time. Complete dentures                            session (final impression) is of the highest importance,
provide a solid rehabilitation for edentulism.                                    as the stability of a complete denture relies on the

              OPEN ACCESS This is an Open Access article under the CC BY-NC 4.0 license.
              Peer-Reviewed Article
    Citation: Pani E, Sarafianou A, Chalazoniti A, Artopoulou II, Polyzois G. Conventional vs simplified complete dentures: a systematic review.
    Stoma Edu J. 2021;8(4):261-274
    Received: November 29, 2021; Revised: December 11, 2021; Accepted: December 24, 2021; Published: December 27, 2021
    *Corresponding author: Dr. Eleftheria Pani, DDS, MSc; Thivon 2, Goudi, Athens, 11527, Greece
    Tel: +306932710055; Fax: +30210645992; e-mail: elpani@dent.uoa.gr
    Copyright: © 2021 the Editorial Council for the Stomatology Edu Journal.




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                    supporting tissues. On the final casts, base plates        simultaneously with the maxillomandibular records.
Review Articles     are fabricated with occlusal rims to proceed with          Previously, with the assistance of a preformed anterior
                    the maxillomandibular records, in order to transfer        tooth arrangement guide (ANTAG) the position of
                    the final casts to the articulator. The try-in of the      the maxillary anterior teeth is defined. The rest of the
                    complete dentures is also a two-stage approach:            teeth will be placed in the laboratory by the technician
                    first only the anterior teeth are placed on the base       who continues with the setting of the denture. In the
                    plates and tried-in and then all of them. After the        following clinical session, the denture is delivered to
                    approval of both clinician and patient, the complete       the patient. Interestingly, in this protocol the patient
                    dentures are processed and delivered to the patient        never tries the dentures with all the teeth before the
                    [2]. This is the conventional technique, which is the      delivery [5]. Ceruti et al. [6] used another version of
                    most widely taught technique for complete dentures         a simplified protocol. This version consists of only
                    worldwide. There is insufficient evidence for the          two clinical sessions and is defined as ‘simplified
                    necessity of the clinical step of the final impression.    edentulous treatment (SET)’. The impression, the
                    Are two impressions -a preliminary and a final one- a      maxillomandibular records, the selection of the teeth
                    prerequisite for the success of a complete denture?        and the try-in of the anterior teeth are performed in
                    This question was the incentive for fabricating            the first clinical session. After that, the technician
                    complete dentures with a simplified technique.             completes the arrangement of the teeth and finalizes
                    There are protocols in the literature which suggest        the denture. Therefore, in the next and last clinical
                    the fabrication of dentures with five, four, three or      session the denture is delivered. This protocol is
                    even two clinical visits. It is worth mentioning that      possible only by using a specific material fabricated
                    combining the two sessions of try-in into one converts     for this purpose, the multilayer impression tray
                    the conventional technique into a five-step procedure.     (MIT) [6,7]. As we can conclude from all the different
                    However, this is still considered conventional. It is,     protocols, there are clinical steps which cannot be
                    therefore, important to clarify which steps are omitted    omitted. So, the steps of at least one impression, the
                    in the simplified technique. As implied before, a          maxillomandibular records, a try-in with all or some of
                    simplified protocol does not include a final impression.   the teeth selected and the delivery cannot be omitted.
                    The five-session simplified protocol is described by       Some of them may be combined in one session, but
                    Lira-Oetiker et al. [3]. The only difference between       they definitely have to be performed. The clarification
                    the two protocols (conventional and simplified) used       of these protocols and their stages are shown in Table
                    in this trial is the omittance of the final impression.    1. The stages of the conventional and the most used
                    Reviewing the literature, the most common simplified       four-session simplified protocols are shown in Fig. 1.
                    protocol used is the four-session one, which includes a    The simplified protocol aims to a shorter procedure
                    preliminary impression, maxillomandibular records, a       of fabrication of the complete denture. Therefore, the
                    try-in, and the complete denture delivery. The majority    use of a facebow and the remount of the denture in
                    of the researchers omit besides the final impression       order to perform selected grinding before delivery,
                    also the second try-in session in the simplified           are usually omitted.
                    protocol. That converts the simplified protocol into a     In order to replace an established protocol with a
                    four-session one. The four-session simplified protocol     new one, it is necessary to have adequate evidence
                    is thoroughly described by Duncan and Taylor [4]. In       that the new protocol offers the same outcome as the
                    the first session the clinician makes an impression of     previous one, if not better. The aim of this systematic
                    alginate using a stock tray, either metallic or plastic.   review is to report on the current evidence and
                    This is the only impression required for the fabrication   evaluate the differences between the simplified and
                    of the complete denture. The prerequisite for this         the conventional method for fabrication of complete
                    simplified technique to be successful is, according        dentures and do a narrative comparison in order to
                    to the writers, the knowledge of the oral anatomy.         conclude if the simplified technique is equal to or
                    The cast produced from this impression is the final        better than the conventional one. The outcomes to
                    cast on which the record bases with the occlusal           be evaluated are masticatory performance and ability,
                    rims are fabricated. The next session is the recording     patient satisfaction, oral health related quality of
                    of the maxillomandibular relationship. In the try-in       life (OHRQoL), denture quality, time, cost, and cost
                    session the clinician and the patient evaluate the         effectiveness. The null-hypothesis is that the simplified
                    aesthetics of the denture and test the phonetics by        protocol results in superior outcomes compared to
                    the pronunciation of specific words and sounds. In         the conventional protocol.
                    order to continue with the delivery of the denture,
                    both the patient and the clinician have to accept the      2. METHODOLOGY
                    denture at this session [4]. Owen and MacEntee [5]         The present systematic review has been conducted
                    described a three-session simplified protocol defined      according to the PRISMA instructions [8]. The protocol
                    as ‘abbreviated complete denture technique’ or             of this systematic review was submitted to PROSPERO
                    ‘minimum acceptable protocol (MAP) for complete            (ID 160603). An electronic search of the MEDLINE-
                    dentures’. According to this, the anterior teeth are       PubMed, Scopus and Europe PMC databases was
                    arranged by the clinician in the second session            conducted by two independent researchers (PE and



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            Conventional vs Simplified Complete Dentures
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                                                                                                                                                                                                                    Review Articles
             Table 1. Stages of conventional and simplified complete denture fabrication protocol.

                                         Conventional protocol                                       Simplified protocol




                                                                                                                                                    Table 1. Stages of conventional and simplified complete denture fabrication protocol.
             Sessions                      6 stages             5 stages             5 stages        4 stages       3 stages        2 stages


             Preliminary                        X                    X                  X               X               X               X
             impression


             Final impression                   X                    X

             Maxillomandibular                  X                    X                  X               X               X               X
             records


             Try-in                             X                                       X                               X               X
             (anterior teeth)


             Try-in                             X                    X                  X               X
             (anterior+posterior
             teeth)
             Delivery                           X                    X                  X               X               X               X

             Comments                         Most            Not common            Lira-Oetiker       Most         Owen &            SET
                                            common                                    et al. [3]     common       MacEntee [5]     Ceruti [6,7]
Figure 1. Flowchart of the conventional and the simplified protocol.
                                                                                        SA). The inclusion criteria were randomized clinical
                                                                                        trials, cohort clinical studies and clinical studies
                 Conventional                               Simplified
                                                            Simplified                  of complete dentures fabricated either with the
                   protocol                                  protocol
                                                             protocol                   conventional or the simplified method. The PICO details
                   6-stage                                   4-stage                    can be seen in Table 2. The PICO question was formed
                                                                                        as such: ‘Does the simplified technique for fabrication
                                                                                        of complete dentures provide equal or even better
              Preliminary Impression                   Preliminary Impression
                                                                                        outcomes to the treatment of the edentulous patients
                                                                                        than the conventional technique?’ All relevant studies
                                                                                        should have been published in English from January
                  Final Impression
                                                                                        1950 to January 2020. The keywords used in the
                                                                                        search included a combination of the following terms:
                                                         Maxillomandibular
                                                                                        Simplified OR conventional (technique OR method OR
                 Maxillomandibular
                       records                                 records                  fabrication OR construction) AND complete dentures
                                                                                        AND patient satisfaction AND/OR cost AND/OR time
                                                                                        AND/OR masticatory ability AND/OR ability to speak
               Try-in (anterior teeth)                                                  AND/OR success of the complete dentures AND/
                                                                                        OR performance ability. The results of the electronic
                                                                                        search were screened based on the relevance of the
                        Try-in                                  Try-in
                                                                                        titles to our topic. Any disagreement between the two
                 (anterior+posterior                     (anterior+posterior            reviewers was solved in consensus by discussion or by
                        teeth)                                  teeth)                  a third reviewer (CA). Articles that appeared multiple
                                                                                        times during the search were considered only once.
                                                                                        Following that, the abstracts of the articles chosen
                        Delivery                                Delivery                were read to identify if they met the inclusion criteria.
                                                                                        The full-text articles were then obtained and reviewed
                                                                                        if this determination could not be made only with
             Figure 1. Flowchart of the conventional and the simplified protocol.       the abstracts.


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                    Articles written in other languages than English and          research has led to newer evidence on the topic since
Review Articles     studies referring to implants, overdentures, immediate        then. Our systematic review aims to overcome this
                    dentures and/or fixed partial dentures were excluded.         limitation and include all the available information.
                    Furthermore, studies that did not compare the two             We included these papers in the discussion section of
                    aforementioned methods were excluded, even if they            the present review in order to compare their results
                    could provide information about each technique                with ours and identify any differences. The flowchart
                    separately.                                                   for the selected articles used in this systematic review
                    The main difference between the two protocols                 can be seen in Fig. 2. The characteristics of the studies
                    -conventional and simplified- is the session of               included are listed in Table 3.
                    the final impression. If the clinician performs two           In the same table the risk of bias of each study
                    impression sessions-one preliminary and one final-            individually is presented. All the included randomized
                    then the protocol used is called conventional. When           studies except for one, were at low risk of bias. For the
                    the clinician takes only one impression from which            study of Krishna et al.. [22] there were some concerns
                    the final casts will be fabricated, then we have the          about the risk of bias. This doubt was raised from the
                    simplified protocol.                                          randomization process because of lack of information.
                    The outcomes evaluated were masticatory performance           The study of Duncan et al. [10] was the only one
                    and ability, patient’s satisfaction, oral health related      evaluated with a different risk of bias assessment
                    quality of life (OHRQoL), denture quality, time, cost,        tool (ROBINS-I). The authors of the present review
                    and cost effectiveness.                                       concluded that the algorithm overestimated the risk
                    As part of the data extraction process, two reviewers         of bias and the overall assessment for this study is
                    (PE, SA) independently assessed the risk of bias in the       ‘no information’ and its results should be presented
                    included studies individually. In the present study,          with precaution.
                    the risk of bias for randomized clinical trials was           Table 4 presents the impression techniques and the
                    assessed according to ROBINS 2 (RoB 2) [9]. The study         different materials used for final impression in each
                    of Duncan et al. [10] was the only study included in          study.
                    this systematic review which was not randomized.              The study of Mengatto et al. [23] could not be
                    Therefore, a different tool for accessing the risk of bias    enlisted in any category of the materials used for the
                    was used (ROBINS-I) [11]. The risk of bias across the         final impression, because the materials used were
                    studies was evaluated by GRADE, which is a system for         not clarified, but rather were mentioned under the
                    rating the quality of a body of evidence in a systematic      general term ‘compound with an impression material’.
                    review [12].                                                  Interestingly, in the test group of the study of the de
                    The different studies included in the present review          Resende et al. [15] group, the baseplate in the clinical
                    examined different factors. Due to this reason, they          session of the try-in was relined with zinc oxide and
                    were compared in subgroups. A statistical analysis of         eugenol. However, the procedure was defined and
                    the results was not feasible.                                 considered as simplified by the authors.
                     Table 2. PICO question.                                      As observed in Table 3, the included studies examined
                                                                                  different variables. In an effort to assess the studies’
                                                                                  outcomes more comprehensively, the different studies
                                                                                  were categorized based on their examined outcomes
                                                                                  (Table 5). It is worth mentioning that five outcomes
                                                                                  were examined only by one different research each.
                                                                                  This probably occurs because the definition of each
                                                                                  outcome differs between the study groups. Therefore,
                                                                                  we included studies, that examined similar variables
                    3. RESULTS                                                    but named them differently, in the same category
                    The electronic search of databases produced 474               in order to draw more robust conclusions (Table 6).
                    titles of articles relevant to the topic. 403 articles were   Komagamine et al. [21] focused on the masticatory
                    duplicated and therefore excluded. After reading the          performance of the patients but the authors also
                    abstracts, 22 articles were rejected because they also        added two extra variables, i.e. the occlusal contact area
                    referred to other prosthetic rehabilitations (apart from      and the maximum occlusal force. According to Lepley
                    complete dentures) such as overdentures and fixed             et al. [28], the greater the occlusal contact and the bite
                    partial dentures. A full text was obtained from the           force, the better the masticatory performance. Horie
                    remaining 49 articles and only 19 of these fulfilled          et al. [29] also exhibited that the occlusal contact and
                    the inclusion criteria. All of the included studies were      the near occlusal contact areas related significantly
                    clinical trials, 18 of which were randomized clinical         with the mixing ability. However, the study involved
                    trials (RCT). The electronic search resulted also in the      dentate patients.
                    identification of two systematic reviews and one meta-        It is evident that the majority of the studies focused
                    analysis on the comparison between the conventional           mainly on aspects of patient quality of life (patient
                    versus the simplified technique for complete denture          satisfaction and OHRQoL).
                    fabrication. Their limitation was that none of these          The quality of evidence in this systematic review was
                    papers examined all the outcomes, but rather they             high for each outcome, mainly due to the low risk of
                    focused on some of them. Furthermore, additional              bias of all but two studies and the homogeneity in



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Conventional vs Simplified Complete Dentures
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their respective design. The fact that all studies did a   stability and comfort of the complete denture. Hyde




                                                                                                                           Review Articles
power analysis to determine the study sample size and      et al. [16] emphasized the impact of the impression
used a level of significance at 5% affected positively     material. His team fabricated two sets of complete
the quality of evidence.                                   dentures for each patient, one obtained after an
                                                           alginate impression and the other obtained from a
3.1. Masticatory performance                               silicone impression. He concluded that the patients
Alves et al. [2] tried to associate the masticatory
                                                           preferred the dentures fabricated from a silicone
ability based on the method used (simplified versus
                                                           impression. All the other studies proved the two
conventional) and on some sociodemographic
                                                           methods to be equal (Komagamine et al. [21], Kawai
characteristics. No difference on masticatory ability
was found between the two techniques. When                 et al. [18,20], Krishna et al. [22], Lira-Oetiker et al. [3],
evaluating the sociodemographic variables, only            Mengatto et al. [23], Nunez et al. [25], Regis et al. [26]).
gender was found to have a statistically significant       The only difference was that the satisfaction increased
difference with women presenting lower masticatory         in both groups respectively following the time and
performance than men.                                      the use of the complete dentures (Nunez et al. [25],
Cuhna et al. [14] differentiated the masticatory           Regis et al. [26]). Kawai et al. [18] on the other hand
ability from the masticatory performance. Although         concluded that there is increase of satisfaction in 3
masticatory performance was measured according             months compared to the baseline, but they found a
to different number of chewing cycles (20 and 40)          significant decrease in 6 months. This phenomenon
the researchers could not find a difference between        was noticed in both categories making them not to
the two groups. However, there was an improvement
                                                           differentiate. It is remarkable that after 10 years Kawai
when the patients with complete dentures chewed
                                                           et al. [20] still found no difference between the control
40 rather than 20 times and this suggests that these
                                                           and test group except for esthetics. Patients with
patients can achieve a good masticatory performance
if they have patience and persistence. Subjectively,       simplified dentures were significantly more satisfied
patients with complete dentures fabricated with            with the maxillary denture’s esthetics after 10 years.
the simplified technique are presumed to have no           Komagamine et al. [21] and Krishna et al. [22] failed
difficulties in mastication in contrary to the control     to prove the improvement over time because of the
group. This was the only difference between the            short-term follow up.
groups which did not affect the overall insignificant
score.                                                     3.3. Oral Health Related Quality of Life (OHRQoL)
Interestingly, Komagamine et al. [21] included as their    The OHRQoL test is performed by a series of
study outcomes the occlusal contact area and the           questionnaires. The basic questions are universal
maximum occlusal force apart from the masticatory          (OHIP-Edent) but every country has added questions
performance. Dentures fabricated by the conventional       relevant to their population and their lifestyle in
method had a statistically higher occlusal contact area
                                                           order to get more specific answers. OHRQoL showed
than the simplified dentures, but this did not relate
                                                           no difference between the two examined methods
with a better mixing of the food. This was attributed
                                                           among all the studies.
to the fact that all the measurements were performed
only 1 month after delivery and this interval may have
been too short and that the final impression may           3.4. Quality of complete dentures
provide more stable acrylic resin bases and occlusion      The complete dentures included in each trial were
rims during the following sessions.                        fabricated by the same technicians, therefore it was
Similar to de Villa Camargos et al. [13], Mengatto         highly improbable to find a difference among the
et al. [23] found no difference in the masticatory         complete dentures. Impeccable proof for this was
performance depending on the protocol used. In             provided by the study group of Kawai et al. [18]. They
other words, there is evidence in all these studies that   let prosthodontists, blinded the trial, to objectively
the method used to fabricate a complete denture does       examine the quality of the dentures and the results
not affect the masticatory performance and ability         were similar for conventional and simplified dentures.
and both techniques are held as equal.
3.2. Patient satisfaction
                                                           3.5. Time
                                                           Five clinical trials focused on the time spent for the
Many studies focused on the patient satisfaction
and the influence that the fabrication method has          treatment plan. Kawai et al. [19] used a more general
on it. Only two of them found a significant difference     term and measured the time spent for the treatment
between the two methods. Jo et al. [17] documented         plan. On the other hand, Ceruti et al. [6] measured
that the conventional method was preferred among           the time needed for each step, such as clinical time,
the patients because the final impression ensured          number of clinical sessions but also the laboratory
more detailed borders and therefore increased              time and the laboratory returns.


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                    The research group of de Resende et al. [15] separated treatment from the time a patient exits their house
Review Article      time in two major categories: the time needed from until their return. Although the interpretation of cost
                    the consultation until the delivery of the dentures differs between the studies, all three came to the same
                    and the time needed for adjustments. If the number conclusion, that conventional method costs more
                    of visits for adjustments was outnumbered for one than the simplified method.
                    method, then this could be a critical clinical issue. Such
                    a differentiation in time was also made by Duncan et 3.7. Cost effectiveness
                    al. [10]. The researchers calculated the visits needed It is rational to think that studies which examined cost
                    toisfabricate
                          the resultthe
                                     of the   divisiondenture
                                          complete       of the cost
                                                                   andbyseparately
                                                                          the satisfaction.
                                                                                         and The
                                                                                              timeauthors
                                                                                                    would haveconcluded  that
                                                                                                                  also evaluated  cost effectiveness.
                    the visits needed for adjustments. The results in both However, the only study group that referred to cost
                       cost effectiveness
                    outcomes                 is higher significant
                                  were statistically     for the conventional
                                                                       favoring group.
                                                                                  the effectiveness was Miyayasu et al. [24]. According to
                    simplified protocol. Krishna et al. [22] limited their them cost effectiveness is a combination of cost and
                    evaluation to the number of visits. Generally, it was patient satisfaction where time is also considered
                       3.8. Need for reline
                    agreed in all studies that the simplified method was under the term of cost. Cost and patient satisfaction
                    faster in clinical time and clinical sessions than the have to be quantified, as cost effectiveness is the result
                    conventional
                       The study by  method.
                                       Duncan et al. [10] was the only one referring     of thetodivision
                                                                                                   the needofofthe   costThis
                                                                                                                 reline.   by the satisfaction. The
                                                                                         authors concluded that cost effectiveness is higher
                       need
                    3.6. Costand more specifically the time when this occurs,for          reflects  not only the group.
                                                                                             the conventional      quality of
                    The cost of denture fabrication was evaluated in
                       the clinical
                    three   denture trials.
                                      but also
                                             All ofthe  effectiveness
                                                     them   agreed that  andtheprecision
                                                                                 cost 3.8. of Need
                                                                                               the impression
                                                                                                     for reline technique.
                    of a conventional method was significantly higher The study by Duncan et al. [10] was the only one
                       Although
                    than   the costtheof thought    is veryone.
                                          the simplified      good    in this
                                                                  Kawai   et al.case,
                                                                                 [19] wereferring
                                                                                           cannot draw
                                                                                                     to theanyneedconclusion
                                                                                                                    of reline. This need and more
                    attributed the difference in cost to the final impression specifically the time when this occurs, reflects not only
                       because
                    step        thethe
                           and to    evaluation
                                         remounthappened       three months
                                                      of the denture     beforeafter
                                                                                  the thethe
                                                                                          delivery.
                                                                                              quality of the denture but also the effectiveness
                    delivery. Miyayasu et al. [24] and Vecchia et al. [27] and precision of the impression technique. Although
                    considered also under the term of cost the time spent the thought is very good in this case, we cannot draw
                    from the professionals. Vecchia et al. [27] evaluated any conclusion because the evaluation happened
                       Figure
                    also       2. Flowchart
                          the time            illustrating
                                     that a patient        studytoselection
                                                        needs      spend for process.
                                                                                their three months after the delivery.

                         Electronic database search:                                    EXCLUDE
                                    5500
                                                                                  Irrelevant titles: 5026


                               Relevant titles: 474


                                                                                   Duplicate titles: 403


                           Records after removal of
                               duplicates: 71
                                                                                   Abstract reading: 22


                          Records after reading the
                                abstracts: 49
                                                                                    Full-text articles: 5


                              Full-text articles: 44




                         Articles included according                       Systematic reviews: 3              Articles relevant to the
                           to inclusion criteria: 19                                                        topic, cannot be included
                                                                                                            according to the inclusion
                                                                                                                     criteria: 22

                     Figure 2. Flowchart illustrating study selection process.




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Conventional vs Simplified Complete Dentures
                                                                                                                         www.stomaeduj.com




                                                                                                                       Review Article
 Table 3. Summary of the study characteristics included in the systematic review.




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 Review Articles




                    S: simplified method, C: conventional method, SET: simplified edentulous treatment, pt: patients, CD: complete denture,
                    PROMs: patient-reported outcome measurements, OHRQoL: Oral Health Related Quality of Life




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                                                                                                                                     Review Articles
Table 4. Impression technique and materials.




               Table 5. Summary of the studies and the outcomes they studied.
 Table 5. Summary of the studies and the outcomes they studied.

                          Outcomes                                                          Studies
 Masticatory performance/ability                                  Alves et al. [2], de Villa Camargos et al. [13], Cuhna et al.
                                                                  [14], Komagamine et al. [21], Mengatto et al. [23]
 Patient satisfaction                                             Ceruti et al. [6], de Villa Camargos et al. [13], de Resende
                                                                  et al. [15], Jo et al. [17], Kawai et al [18], Kawai et al [20],
                                                                  Krishna et al. [22], Lira-Oetiker et al. [3], Nunez et al. [25],
                                                                  Regis et al. [26]
 OHRQoL                                                           de Villa Camargos et al. [13], de Resende et al. [15],
                                                                  Hyde et al. [16], Jo et al. [17], Kawai et al. [20], Nunez et
                                                                  al. [25], Regis et al. [26]
 Denture Quality                                                  Ceruti et al. [6], de Resende et al. [15], Kawai et al. [18],
                                                                  Regis e al. [26]
 Time                                                             Ceruti et al. [6], de Resende et al. [15], Duncan et al. [10],
                                                                  Krishna et al. [22], Kawai et al. [19]
 Cost                                                             Kawai et al. [19], Miyayasu et al. [24], Vecchia et al. [27]
 Comfort/stability/esthetics/ability to speak/ease to             Hyde et al. [16], Kawai et al. [18], Kawai et al. [20], Lira-
 clean/ability to chew specific foods                             Oetiker et al. [3], Mengatto et al. [23]
 Complete dentures’ functional activity                           de Villa Camargos et al. [13]
 Clinical outcomes                                                de Resende et al. [15]
 Occlusal contact area/maximum occlusal force                     Komagamine et al. [21]
 Cost effectiveness                                               Miyayasu et al. [24]
 Need for reline                                                  Duncan et al. [10]
 Impressions                                                      Hyde et al. [16], Krishna et al. [22]



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               Table 6. Summary of the studies and the outcomes they studied revisited.
                                                                                                                                     269
                     Need for reline                                                     Duncan et al. [10]
                     Impressions                                                         Hyde et al. [16], Krishna et al. [22]
                    Pani E, et al.
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                                     Table 6. Summary of the studies and the outcomes they studied revisited.
Review Article       Table 6. Summary of the studies and the outcomes they studied revisited.

                                              Outcomes                                                             Studies
                     Masticatory performance/ability, Occlusal contact                   Alves et al. [2], de Villa Camargos et al. [13], Cuhna et al.
                     area/maximum occlusal force                                         [14], Komagamine et al. [21], Mengatto et al. [23]
                     Patient satisfaction, Comfort/stability/esthetics/ability to        Ceruti et al. [6], de Villa Camargos et al. [13], de Resende
                     speak/ease to clean/ability to chew specific foods                  et al. [15], Hyde et al. [16], Jo et al. [17], Kawai et al. [18],
                                                                                         Kawai et al. [20], Krishna et al. [22], Lira-Oetiker et al. [3],
                                                                                         Mengatto et al. [23], Nunez et al. [25], Regis et al. [26]
                     OHRQoL                                                              de Villa Camargos et al. [13], de Resende et al. [15],
                                                                                         Hyde et al. [16], Jo et al. [17], Kawai et al. [20], Nunez et
                                                                                         al. [25], Regis et al. [26]
                     Denture Quality, Complete dentures’ functional activity,            Ceruti et al. [6], de Resende et al. [15], Kawai et al. [18],
                     Clinical outcomes                                                   Regis et al. [26], de Villa Camargos et al. [13]
                     Time                                                                Ceruti et al. [6], Duncan et al. [10], de Resende et al. [15],
                                                                                         Kawai et al. [19], Krishna et al. [22]
                     Cost                                                                Kawai et al. [19], Miyayasu et al. [24], Vecchia et al. [27]
                     Cost-effectiveness                                                  Miyayasu et al. [24]
                     Need of reline                                                      Duncan et al. [10]
                     Impressions                                                         Hyde et al. [16], Krishna et al. [22]

                    4. DISCUSSION                                                      ridge height and patient satisfaction which comes
                                                                                       in agreement with our result. The included studies
                    4.1. Masticatory performance                                       did not evaluate patient satisfaction based only on
                    The primary goal when fabricating a denture is to
                                                                                       the denture fabrication technique, but also assessed
                    evaluate the patients’ masticatory performance.
                    The comparison of the two methods could not omit                   all other factors that may influence it, such as the
                    the evaluation of the masticatory performance. This                remaining ridge height. No differences in patient
                    evaluation is objective and subjective. Interestingly              satisfaction were found between all the included
                    the results of the objective and subjective test do not            groups.
                    always coincide. In other words, there is a difference
                    between the masticatory performance and the                        4.4. Oral Health Related Quality of Life (OHRQoL)
                    assessment of their chewing ability [30]. The level of
                                                                                       Following patient satisfaction, the oral health related
                    bone resorption did not influence the masticatory
                    ability of the patients according to Marcello-Machado              quality of life (OHRQoL) was examined. OHRQoL was
                    et al. [31]. This is in agreement with the results of the          measured using different versions of the Oral Health
                    study of Alves et al. [2] and our results.                         Impact Profile (OHIP). OHIP-Edent is a shortened
                    4.2. Classification systems of complete edentulism                 version of OHIP and focused on the edentulous
                    The majority of the studies included used the                      patients. Moreover, OHIP-Edent can detect the
                    classification system for complete edentulism of the               differences in the quality of life of the patients after
                    American College of Prosthodontics (ACP) [32]. They
                                                                                       recieving a new rehabilitation. De Souza et al. [36]
                    focused on the ridge resorption as the main factor
                    of a compromised case. However, this classification                proved the validity of the Brazilian version of the OHIP-
                    system categorizes the edentulous patients based on                Edent as well as the validity of the Geriatric Oral Health
                    the complexity of the case which depends not only                  Assessment (GOHAI). They compared the answers of
                    by the residual ridge. Only a minority belonged to                 these two OHRQoL inventories with the answers of a
                    the most favorable class (class I). This indicates that            denture satisfaction questionnaire and they found a
                    the results are not biased as they would have been                 strong correlation [36]. Likewise, Sato et al. [37] found
                    if only patients with the most ideal oral condition
                                                                                       that the Japanese version of OHIP-Edent (OHIP-Edent
                    were included [32]. Lira-Oetiker et al. [3] used the
                    classification system of Cawood and Howell [33] and                J) demonstrated good reliability and validity [37].
                    included patients of class II, III and IV. We could imply          It is important to mention the study of Stober et al.
                    that the results may be optimized [33].                            [38]. They correlated OHRQoL measured with OHIP-
                                                                                       Edent with the patient satisfaction measured with
                    4.3. Patient satisfaction                                          questionnaires. Although they emphasized that
                    Huumonen et al. [34] indirectly associated the ridge               patient satisfaction cannot per se predict the OHRQoL,
                    resorption with the patient satisfaction. In their study
                                                                                       they found a significant association between the two
                    patients with severe ridge resorption complained
                    about the stability of the mandibular denture and                  factors [38], strengthening the conclusion that the
                    that caused reduced satisfaction. Instead, Pan et al.              method used did not affect either the OHRQOL or the
                    [35] did not find a significant association between                patient satisfaction.


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4.5. Cost and time                                             and Souza [44] provided the answer with their study




                                                                                                                            Review Article
The simplified and the conventional technique differed         where the only difference between the two groups
significantly in two outcomes, named cost and time.            was the use of the facebow. According to them the
The simplified technique did have a significant lower          complete dentures fabricated without the use of
cost than the conventional technique. The cost of              the facebow were better than the dentures of the
the conventional is higher as the clinicians use extra         control group, proving that a complete denture can
materials. The session of the final impression includes        also be fabricated with simple methods avoiding the
an acrylic resin custom tray, a compound for border            use of a facebow. The differences found between the
molding and a wash material. The use of these three            two groups were also attributed to the fact that the
additional materials inevitably increases the cost [39].       mandibular cast of the control group was articulated
The time needed for the conventional technique was             with centric, lateral and protrusive records. This is very
longer, since the protocol included an extra clinical          demanding especially in edentulous patients where
session. The time increases more if we take into               the records are made with record bases and occlusal
consideration the difficulty of the final impression.          rims which are impossible to be stable during the
Moreover, a randomized clinical trial of Kimoto et al.         procedure [44].
[40] revealed a difference in time needed based on
the experience. Although Kimoto et al. [40] did not            4.9. Remount
mention the years of experience of each clinician, the         A valid evaluation about the importance of the
time difference in the stage of the final impression           remount could occur if that was the only difference
was statistically significant [40]. In the studies             between the control and the test group. Such a study
included in the present review, the practitioners              was performed by Shigli et al. [45] and they found
varied from undergraduate students to experienced              the statistically significant superiority of the remount
prosthodontists. No study compared students and                process. The patients of the test group needed less
prosthodontists directly. That means that the time             post-insertion visits, experienced less pain and
difference was valid in all studies regardless of the          discomfort during mastication and presented less
clinician and therefore the simplified method is quicker.      sore spots. In the present review such a difference
                                                               was not noticed. However, we have to see this result
4.6. Cost effectiveness                                        with precaution as the influence of the remount could
Cost effectiveness analysis is an economic analysis            be lost among the influence of other factors.
which aims to give an answer between alternative
treatments. Its calculation is mathematical [41]. The          4.10. Systematic reviews and meta-analysis
simplified technique differs from the conventional             Paulino et al. [46] concluded that the simplified
only in terms of cost and time. This could lead to the         technique does not compromise patient satisfaction
assumption that the simplified technique is more               and masticatory ability with the complete dentures,
cost effective. However, the analysis revealed the             nor does it affect the quality of the denture. Ye et al.
superiority of the conventional method. Only one               [47] found differences between the two techniques
study examined this factor and therefore we cannot             only in cost and time. The most recent-in the searching
draw a conclusion.                                             period of the present review- publication comparing
                                                               the two methods is a meta-analysis of Al- Ansari et al.
4.7. Post-insertion visits and need for reline                 [48]. They included 11 studies and drew conclusions
Duncan et al. [10] concluded that the simplified               about patient satisfaction, quality of life, cost, and
technique required less visits for the necessary               time. For the first two outcomes the researchers
adjustments and there was no difference in the need            found no statistically significant difference between
for reline. During the first three months patients still try   conventional and simplified technique contrary to
to adjust to the new rehabilitation so it is impossible        the other two. The results of our systematic review
to testify the need for reline. Less post-insertion visits     are more comprehensive and they are in agreement
for the simplified technique may be explained by the           with the results of the aforementioned studies. Cost
fact that the final impression with border molding             and time are the only outcomes with a difference
leads often to overextended dentures.                          in favor of the simplified dentures. Apart from that,
                                                               conventional and simplified method of fabrication of
4.8. Facebow                                                   complete dentures have equal outcomes.
In a lot of studies in the intervention group face bow
record was also omitted besides the final impression.          4.11. Limitations
Farias-Neto et al. [42] and Prakash et al. [43] concluded      There is also a lot of heterogeneity among the studies
in their systematic review accordingly that the use of         because of the different materials used, the different
a face bow does not result in a better outcome for the         factors examined with a variety of tests, the differences
complete dentures. This comes in agreement with                between the groups, the level of experience of the
our results, but it logically raises the question if the       clinician and the short follow up.
results are valid as there is no included study which          CAD/CAM complete dentures are out of the scopus
examines the use or not of only the facebow. Kumar             of the present review.


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                    Pani E, et al.
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                    5. CONCLUSION                                                              anatomy. Moreover, there is the need to establish a
Review Article
                                                                                               standarised simpliefied protocol in order to consider
                    The conclusions of the present systematic review are                       it as an alternative.
                    the following:
                    1. Our systematic review is in agreement with the                          CONFLICTS OF INTEREST
                                                                                               The authors declare no conflict of interest.
                    literature of the topic.
                    2. The null-hypothesis was confirmed in terms of cost                      AKNOWLEDGEMENTS
                    and time but rejected in all the other factors.                            Special thanks to Dr. Pinelopi Pani, Clinical Associate Professor in
                    3. Cost and time differed significantly between the two                    Henry M. Goldman School of Dental Medicine, Boston University,
                                                                                               Boston, MA 02118, USA, for editing and reviewing this systematic
                    methods favoring the simplified protocol.                                  review.
                    4. Masticatory performance and ability, patient
                    satisfaction, Oral Health Related Quality of Life                          AUTHOR CONTRIBUTIONS
                    (OHRQoL) and denture quality are not affected by                           GP, EP: conceptualization. EP: methodology, software. EP, AS, GP:
                                                                                               validation. EP, AS, GP: formal analysis. EP, IA: investigation. EP, AS,
                    the method of fabrication.                                                 AC: resources. EP, AC, IA: data curation. EP: writing-original draft
                    5. The impression of the edentulous jaw is not a simple                    preparation. EP, AS, GP: writing-review and editing. GP: visualization.
                    task and requires profound knowledge of the oral                           AS: supervision. GP: project administration.
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Stoma Edu J. 2021;8(4): 261-274                                                               pISSN 2360-2406; eISSN 2502-0285                      273
                    Pani E, et al.
www.stomaeduj.com

Review Article
                                                                                                          Eleftheria PANI
                                                                                                                    DDS, MSc
                                                                                              Department of Prosthodontics
                                                                                                          School of Dentistry
                                                                               National and Kapodistrian University of Athens
                    CV                                                                                       Athens, Greece
                    Eleftheria Pani graduated from the Dental School of the National and Kapodistrian, University of Athens, Athens, Greece in 2014.
                    She was accepted in the postgraduate program of Prosthodontics in the National and Kapodistrian University of Athens, Athens,
                    Greece from which she graduated in 2021 after presenting her master thesis.




                    Questions
                    1. What is the difference between conventional and simplified complete dentures?
                    q a. Ommitance of the final impression;
                    q b. Ommitance of the final impression and the try-in;
                    q c. The use of different materials;
                    q d. Ommitance of laboratory stages.
                    2. What is mainly used as impression material for the simplified complete dentures?
                    q a. Alginate;
                    q b. Silicone;
                    q c. Polyether;
                    q d. Compound.
                    3. Simplified complete dentures differ significantly from the conventional in:
                    q a. Cost;
                    q b. Cost and time;
                    q c. Cost, time, patient satisfaction;
                    q d. Cost, time, patient satisfaction, OHRQoL.
                    4. The majority of the studies examined:
                    q a. Cost and time;
                    q b. Patient satisfaction;
                    q c. Patient satisfaction and OHRQoL;
                    q d. Cost, time, patient satisfaction and OHRQoL.




 274                Stoma Edu J. 2021;8(4): 261-274                                                    pISSN 2360-2406; eISSN 2502-0285