
Stoma Edu J. 2024;11(1-2):
pISSN 2360-2406; eISSN 2502-0285
www.stomaeduj.com
Original Articles
58-64
ensuring optimal outcomes for patients with
malocclusion. This research would contribute to
the existing literature by better understanding the
MF position of dierent sagittal and vertical skeletal
malocclusion. Moreover, Knowing the location of
the mental foramen in each malocclusion is crucial
during the insertion of mini plates and mini-screws.
High-resolution Cone-Beam Computed Tomography
(CBCT) is considered the most promising and
accurate technology currently available for precisely
determining the position of the mental foramen
quantitatively [7]. By examining CBCT images,
researchers could assess the MF position and analyse
any correlations between its location and dierent
malocclusion classes.
This observational study aimed to determine and
compare the size and location of the MF by using the
CBCT in class I, II, and III malocclusions in horizontal
and vertical growth pattern samples.
2. METHODS AND MATERIALS
In this study, a comprehensive analysis was
conducted on CBCT obtained from the archives of
the Department of Oral and Maxillofacial Radiology
at the Faculty of Dentistry, Tehran Medical Sciences,
Islamic Azad University, Tehran, Iran. The survey
was performed according to the guidelines of
the Declaration of Helsinki. All human research
was conducted by the ethical standards of the
committee responsible for human experimentation
(institutional and national) and with the Helsinki
Declaration of 1975, revised in 2013. 150 CBCT
Images, aged between 18 and 35, were collected
with Class I, II, and III malocclusions with vertical
and horizontal growth patterns in each sagittal
malocclusion. Using the Analysis Power ANOVA one-
way considering α=0.05 and β=0.2, the minimum
required sample size for each of the six subgroups
under investigation is determined to be 25 samples.
Therefore, 150 individuals (25 with vertical growth
patterns and 25 with horizontal growth patterns
in each class I, II, and III malocclusion group). Each
individual has two mental foramina; therefore,
considering 150 samples, 300 foramina were
examined. All the patients had no specic oral
diseases, surgical history, previous orthodontic
treatment, previous history of trauma, and facial and
neck anomalies.
Ethical approval was obtained from the IAU Local
Research Ethics Committees (Number: IR.IAU.
DENTAL, REC;1400.187). The skeletal malocclusion
types were grouped as Class 1, Class 2 and Class 3
according to Steiner's ANB angle and wits appraisal
based on lateral cephalometric radiographs (Point A:
the deepest anterior point on the buccal face of the
maxilla body, Point N: Nasion, Point B: the deepest
anterior point on the buccal face of the mandibular
body, ANB angle: the angle formed by the NA and
NB planes and wits appraisal: which was measured
drawing perpendiculars from points A and B on the
maxilla and mandible, respectively, onto the occlusal
plane).
Class 1: ANB° = 0° to 4°; 0 <Wits<-1
Class 2: ANB°> 4°; 0<Wits
Class 3: ANB°<0°; Wits < -1
Samples in each class I, II, and III groups were divided
into subgroups according to vertical and horizontal
growth. In the horizontal growth pattern, the SN-Gn-
Go angle is less than 32 degrees (32>SN-Gn-Go). In
the vertical growth pattern, the Go-Gn-SN angle is
greater than 32 degrees (Go-Gn-SN>32).
There were 100 images of individuals with Class I
malocclusion, with 25 individuals having a vertical
growth pattern and 25 having a horizontal growth
pattern. For Class II malocclusion, there were 50
images, with 25 individuals having a vertical growth
pattern and 25 individuals having a horizontal
growth pattern. Similarly, there were 50 images
for Class III malocclusion, with 25 individuals with
a vertical growth pattern and 25 with a horizontal
growth pattern. Using CBCT images, measurements
were performed on both the left and right sides. MF
Shape and MF Position relative to the Nearest Tooth
were evaluated. MF Length, Height, Distance from
MF to Inferior Border, Distance from MF to Bone
Crest, and Mental Canal Angle were measured.
The measurements were recorded as follows:
• Mental Foramen Shape: In CBCT images, the shape
of the mental foramen was categorised as oval or
round.
• Mental Foramen Position relative to the Nearest
Tooth: In CBCT images, the position of the mental
foramen was recorded in one of four locations:
below the rst premolars, below the second
premolars, between the rst and second premolars,
and between the second premolars and rst molars.
• Mental Foramen Length: The widest part of the
mental foramen in millimetres.
• Mental Foramen Height: The tallest height of the
mental foramen in millimetres.
• Distance to Inferior Border: The distance from the
lowest point of the foramen to the inferior border of
the mandible in millimetres.
• Distance to Bone Crest: The distance from the
highest point of the foramen to the bone crest in
millimetres.
• Mental Canal Angle with Buccal Surface of
Mandible: The angle between the longitudinal axis
of the mental canal and the superior part of the
buccal cortical bone, measured in degrees.
To assess the reliability of the measurements in the
study, 20 CBCT images were randomly selected, and
the measurements were repeated after one week.
The results of the intraclass correlation coecient
(ICC) test showed no statistically signicant
dierence between the two measurement sessions
(ICC = 0.756)
The data were analysed using the statistical software
SPSS (version 25.0). The mean and standard deviation
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